abstract：BACKGROUND:Increased serum leptin concentration has been linked to increased ventilation in patients with mild heart failure (HF). However, in animal models the absence of leptin has also been associated with increased ventilation. This study evaluated the relationship of circulating leptin concentration with exercise ...

journal_title：Journal of cardiac failure

authors： Cundrle I Jr,Somers VK,Singh P,Johnson BD,Scott CG,Olson LJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:A hallmark characteristic of heart failure (HF) is reduced physical activity (PA) patterns. The relationship between key cardiopulmonary exercise testing (CPX) variables and PA patterns has not been investigated. Therefore, we evaluated PA patterns in patients with ischemic HF and its relationship to peak ox...

journal_title：Journal of cardiac failure

authors： da Silva VZ,Lima AC,Vargas FT,Cahalin LP,Arena R,Cipriano G Jr

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Treatment with specific beta-blockers and doses recommended by guidelines is often not achieved in practice. We evaluated an intervention directed to the pharmacy to improve prescribing. METHODS AND RESULTS:We conducted a pragmatic cluster-randomized trial, where facilities (n = 12) with patients (n = 220) ...

journal_title：Journal of cardiac failure

authors： McCarren M,Furmaga E,Jackevicius CA,Sahay A,Coppler TL,Katzianer J,Griffiths RL,Tonnu-Mihara I,Heidenreich P

更新日期：2013-08-01 00:00:00

abstract：:The complexity of standard medical treatment for heart failure is growing, and such therapy typically involves 5 or more different medications. Given these pressures, there is increasing interest in harnessing cardiovascular biomarkers for clinical application to more effectively guide diagnosis, risk stratification, ...

journal_title：Journal of cardiac failure

authors： Fiuzat M,O'Connor CM,Gueyffier F,Mascette AM,Geller NL,Mebazaa A,Voors AA,Adams KF,Piña IL,Neyses L,Muntendam P,Felker GM,Pitt B,Zannad F,Bristow MR

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Cardiac magnetic resonance (CMR) imaging is an established method of detecting myocardial fibrosis related to prognosis in patients with dilated cardiomyopathy (DCM). Recent studies have found that (99m)Tc-methoxy-isobutyl-isonitrile (MIBI) and (123)I-15-(p-iodophenyl)-3(R,S)-methylpentadecanoic acid (BMIPP)...

journal_title：Journal of cardiac failure

authors： Yoshida A,Takano H,Asai K,Yasutake M,Amano Y,Kumita S,Shimizu W,Mizuno K

更新日期：2013-07-01 00:00:00

abstract：AIMS:Augmented peripheral chemoreflex response is an important mechanism in the pathophysiology of chronic heart failure (CHF). This study characterizes prevalence and clinical predictors of this phenomenon in optimally managed male CHF patients, and seeks to describe the hemodynamic consequences of chemoreceptor hyper...

journal_title：Journal of cardiac failure

authors： Niewinski P,Engelman ZJ,Fudim M,Tubek S,Paleczny B,Jankowska EA,Banasiak W,Sobotka PA,Ponikowski P

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Digitalis glycosides are known to improve the hemodynamic and neurohormonal perturbations that contribute to heart failure (HF)-induced renal dysfunction (RD). The objective of this study was to determine if randomization to digoxin is associated with improvement in renal function (IRF) and to evaluate if pa...

journal_title：Journal of cardiac failure

authors： Testani JM,Brisco MA,Tang WH,Kimmel SE,Tiku-Owens A,Forfia PR,Coca SG

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Empirical evidence supporting the benefits of dietary recommendations for patients with advanced heart failure is scarce. We prospectively evaluated the relation of dietary habits to pre-transplant clinical outcomes in the multisite observational Waiting for a New Heart Study. METHODS AND RESULTS:A total of...

journal_title：Journal of cardiac failure

authors： Spaderna H,Zahn D,Pretsch J,Connor SL,Zittermann A,Schulze Schleithoff S,Bramstedt KA,Smits JM,Weidner G

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Right ventricular failure (RVF) after left ventricular assist device (LVAD) implantation results in significant morbidity and mortality. Preoperative parameters from transthoracic echocardiography (TTE) that predict RVF after LVAD implantation might identify patients in need of temporary or permanent right v...

journal_title：Journal of cardiac failure

authors： Raina A,Seetha Rammohan HR,Gertz ZM,Rame JE,Woo YJ,Kirkpatrick JN

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Relative effectiveness of carvedilol and metoprolol succinate has never been compared in patients with heart failure (HF). METHODS AND RESULTS:From January 1998 to December 2008, 3,716 consecutive patients with ejection fraction (EF) ≤40%, initiated and maintained on carvedilol or metoprolol succinate, were...

journal_title：Journal of cardiac failure

authors： Shore S,Aggarwal V,Zolty R

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Left ventricular assist device (LVAD) support as bridge to recovery (BTR) is uncommon for subjects with chronic heart failure. Myocardial recovery is more evident in recent onset nonischemic cardiomyopathy (ROCM); however, the prevalence of BTR in this subset has not been addressed. METHODS AND RESULTS:We e...

journal_title：Journal of cardiac failure

authors： Boehmer JP,Starling RC,Cooper LT,Torre-Amione G,Wittstein I,Dec GW,Markham DW,Zucker MJ,Gorcsan J 3rd,McTiernan C,Kip K,McNamara DM,IMAC Investigators.

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Fatigue is a prominent and poorly understood symptom of heart failure with reduced ejection fraction (HFrEF). The purpose of this study was to determine whether fatigue correlated with immune biomarkers and prognosis. METHODS/RESULTS:In patients with HFrEF (N = 59) and healthy controls (N = 25), we prospect...

journal_title：Journal of cardiac failure

authors： Fink AM,Gonzalez RC,Lisowski T,Pini M,Fantuzzi G,Levy WC,Piano MR

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Pulmonary restriction-a reduction of lung volumes-is common in heart failure (HF), rendering severity grading of chronic obstructive pulmonary disease (COPD) potentially problematic in subjects with both diseases. We compared pulmonary function in patients with either HF or COPD, or the combination to assess...

journal_title：Journal of cardiac failure

authors： Güder G,Rutten FH,Brenner S,Angermann CE,Berliner D,Ertl G,Jany B,Lammers JW,Hoes AW,Störk S

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Clinical multistage risk assessment associated with electrocardiogram (ECG) and NT-proBNP may be a feasible strategy to screen hypertrophic cardiomyopathy (HCM). We investigated the effectiveness of a screening based on ECG and NT-proBNP in first-degree relatives of patients with HCM. METHODS AND RESULTS:A ...

journal_title：Journal of cardiac failure

authors： Fernandes F,Arteaga-Fernandez E,Antunes Mde O,Buck P,Marsiglia JD,Matsumoto A,Nastari L,Krieger JE,Pereira AC,Mady C

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The total artificial heart (TAH) replaces the heart with 2 pneumatic pumps and 4 tilting disk mechanical valves. It was hypothesized that patients receiving TAH support have persistent hemolysis that resolves after heart transplantation (HT). METHODS AND RESULTS:Hematocrit (HCT) was compared in patients on ...

journal_title：Journal of cardiac failure

authors： Mankad AK,Tang DG,Clark WB,Flattery M,Harton S,Katlaps GJ,Stribling WK,Cooke RH,Hess ML,Kasirajan V,Shah KB

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Recovery of ventricular function during left ventricular assist device (LVAD) support allowing device explantation occurs infrequently. We explored the hypothesis that certain patient profiles are more likely to exhibit LV recovery during LVAD support. METHODS AND RESULTS:A retrospective analysis of data fr...

journal_title：Journal of cardiac failure

authors： Goldstein DJ,Maybaum S,MacGillivray TE,Moore SA,Bogaev R,Farrar DJ,Frazier OH,HeartMate II Clinical Investigators.

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Familial involvement is common in dilated cardiomyopathy (DCM) and >40 genes have been implicated in causing disease. However, the role of genetic testing in clinical practice is not well defined. We examined the experience of clinical genetic testing in a diverse DCM population to characterize the prevalenc...

journal_title：Journal of cardiac failure

authors： Lakdawala NK,Funke BH,Baxter S,Cirino AL,Roberts AE,Judge DP,Johnson N,Mendelsohn NJ,Morel C,Care M,Chung WK,Jones C,Psychogios A,Duffy E,Rehm HL,White E,Seidman JG,Seidman CE,Ho CY

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The clinical consequences of prehospital delay in heart failure (HF) patients are unknown. This study explores the relationship between prehospital delay of HF patients and length of hospital stay, plasma values of brain natriuretic peptides (BNP) as well as the association of delay with all-cause mortality,...

journal_title：Journal of cardiac failure

authors： Johansson P,van der Wal M,van Veldhuisen DJ,Jaarsma T

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:There are little data on the optimization of high-intensity aerobic interval exercise (HIIE) protocols in patients with chronic heart failure (CHF). Therefore, we compared acute cardiopulmonary responses to 4 different HIIE protocols to identify the optimal one. METHODS AND RESULTS:Twenty men with stable sy...

journal_title：Journal of cardiac failure

authors： Meyer P,Normandin E,Gayda M,Billon G,Guiraud T,Bosquet L,Fortier A,Juneau M,White M,Nigam A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Diabetes is associated with increased risk of mortality in heart failure. We examined the association of diabetes with expenditures, hospitalizations, and procedures among Medicare beneficiaries with heart failure during the last 6 months of life. METHODS AND RESULTS:In a 5% national Medicare sample, the pr...

journal_title：Journal of cardiac failure

authors： Blecker S,Herbert R,Brancati FL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Activated vitamin D analog, paricalcitol, has been shown to attenuate the development of cardiac hypertrophy in Dahl salt sensitive (DSS) rats. To determine whether an antihypertrophic effect is class specific, we tested if doxercalciferol (a pro-hormone vitamin D2 analog) could also attenuate the developmen...

journal_title：Journal of cardiac failure

authors： Choi JH,Ke Q,Bae S,Lee JY,Kim YJ,Kim UK,Arbeeny C,Thadhani R,Kang PM

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Enzyme replacement therapy (ERT) for infantile-onset Pompe disease effectively reduces the left ventricular (LV) mass. This study sought to explore detailed process of LV reverse remodeling after ERT with the use of tissue Doppler and stain rate imaging. METHODS AND RESULTS:Nine infants and children with Po...

journal_title：Journal of cardiac failure

authors： Chen CA,Chien YH,Hwu WL,Lee NC,Wang JK,Chen LR,Lu CW,Lin MT,Chiu SN,Chiu HH,Wu MH

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Pregnancy-associated plasma protein A (PAPP-A) proteolyzes insulin-like growth factor (IGF)-binding proteins and thus increases IGF-1 bioactivity. PAPP-A has been reported to be involved in various pathophysiologic abnormalities; however, the clinical significance of PAPP-A has not been examined in cases of ...

journal_title：Journal of cardiac failure

authors： Funayama A,Shishido T,Netsu S,Ishino M,Sasaki T,Katoh S,Takahashi H,Arimoto T,Miyamoto T,Nitobe J,Watanabe T,Kubota I

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:In patients admitted for heart failure (HF), unrecognized elevation of left ventricular end-diastolic pressure (LVEDP) at the time of discharge may have a role in the high rehospitalization rate for HF on follow-up. METHODS AND RESULTS:In a small, prospective study (n = 50), patients admitted for HF were ra...

journal_title：Journal of cardiac failure

authors： Sharma GV,Woods PA,Lindsey N,O'Connell C,Connolly L,Joseph J,McIntyre KM

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Exercise training is included in cardiac rehabilitation programs to enhance physical capacity and cardiovascular function. Among the existing rehabilitation programs, exercises in water are increasingly prescribed. However, it has been questioned whether exercises in water are safe and relevant in patients w...

journal_title：Journal of cardiac failure

authors： Teffaha D,Mourot L,Vernochet P,Ounissi F,Regnard J,Monpère C,Dugué B

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Gamma-glutamyltransferase (GGT) and total bilirubin (T-Bil) are elevated and of prognostic significance in chronic heart failure (CHF). This study sought to compare these novel cardiovascular risk markers in CHF. METHODS AND RESULTS:We evaluated 1,087 ambulatory patients from our heart failure program. Long...

journal_title：Journal of cardiac failure

authors： Ess M,Mussner-Seeber C,Mariacher S,Lorsbach-Koehler A,Pachinger O,Frick M,Ulmer H,Poelzl G

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Left ventricular assist devices (LVADs) are increasingly used to treat patients with refractory heart failure. Current-generation LVADs have major limitations, including the need for open chest surgery, limiting their widespread use. We hypothesized that the aortoatrial continuity could be used as a unique a...

journal_title：Journal of cardiac failure

authors： Friedman PA,Kushwaha SS,Bruce CJ,Park SJ,Ladewig DJ,Mikell SB,Johnson SB,Suddendorf SH,Danielsen AJ,Asirvatham SJ

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:There have been no published recommendations about staffing needs for a heart failure (HF) clinic or an office setting focused on heart transplant. The goal of this survey was to understand the current staffing environment of HF, transplant, and mechanical circulatory support device (MCSD) programs in the Un...

journal_title：Journal of cardiac failure

authors： Jessup M,Albert NM,Lanfear DE,Lindenfeld J,Massie BM,Walsh MN,Zucker MJ,ACCF Heart Failure and Transplant Committee.,AHA Heart Failure and Transplantation Committee.,Heart Failure Society of America.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Sleep-disordered breathing (SDB) is common in patients with reduced ejection fraction (EF). However, little is known about the prevalence of SDB in a general heart failure population including patients with preserved EF (HFPEF). METHODS:We prospectively enrolled stable heart failure outpatients from our hea...

journal_title：Journal of cardiac failure

authors： Herrscher TE,Akre H,Øverland B,Sandvik L,Westheim AS

更新日期：2011-05-01 00:00:00

abstract：INTRODUCTION:This study was designed to determine if physicians' attitudes and recommendations surrounding implantable cardioverter-defibrillators (ICDs) are regionally associated with ICD use. METHODS AND RESULTS:A national sample of 9969 members of the American College of Cardiology was surveyed electronically. Resp...

journal_title：Journal of cardiac failure

authors： Matlock DD,Kutner JS,Emsermann CB,Al-Khatib SM,Sanders GD,Dickinson LM,Rumsfeld JS,Davidson AJ,Crane LA,Masoudi FA

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Drug-related negative outcomes (DNOs) are health problems that patients experience due to drug use or nonuse. Heart failure (HF) patients are at high risk of experiencing DNOs owing to polypharmacy, comorbidities, and age. METHODS AND RESULTS:Ninety-seven consecutive HF patients were enrolled and followed f...

journal_title：Journal of cardiac failure

authors： Gastelurrutia P,Benrimoj SI,Espejo J,Tuneu L,Mangues MA,Bayes-Genis A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The role of matrix metalloproteinases (MMPs) polymorphisms on heart failure (HF) susceptibility, phenotypic characteristics, and prognosis has been poorly explored. METHODS AND RESULTS:We studied 313 HF patients with left ventricular systolic dysfunction and 367 healthy control subjects. Genotyping of MMP-1...

journal_title：Journal of cardiac failure

authors： Velho FM,Cohen CR,Santos KG,Silvello D,Martinelli N,Biolo A,Clausell N,Rohde LE

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Epidemiological studies typically diagnose heart failure (HF) at the time of hospitalization, and have not evaluated the prevalence of HF symptoms in CKD patients without a prior HF diagnosis. METHODS AND RESULTS:We modified the Kansas City Cardiomyopathy Questionnaire (KCCQ) to detect and quantify symptoms...

journal_title：Journal of cardiac failure

authors： Shlipak MG,Lash JP,Yang W,Teal V,Keane M,Cappola T,Keller C,Jamerson K,Kusek J,Delafontaine P,He J,Miller ER 3rd,Schreiber M,Go AS,CRIC Investigators.

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Worsening renal function (WRF) and hypokalemia related to diuretic use for acute decompensated heart failure (ADHF) are common and associated with poor prognosis. Low-dose dopamine infusion improves renal perfusion; its effect on diuresis or renal function specifically in ADHF is not known. METHODS AND RESU...

journal_title：Journal of cardiac failure

authors： Giamouzis G,Butler J,Starling RC,Karayannis G,Nastas J,Parisis C,Rovithis D,Economou D,Savvatis K,Kirlidis T,Tsaknakis T,Skoularigis J,Westermann D,Tschöpe C,Triposkiadis F

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:We examined the validity of leg-to-leg bioelectrical impedance analysis (BIA) and near-infrared interactance (NIR) to assess body composition in chronic heart failure (CHF) patients. METHODS AND RESULTS:A total of 140 patients with CHF were enrolled in this cross-sectional study between June 2008 and July 2...

journal_title：Journal of cardiac failure

authors： Oreopoulos A,Kalantar-Zadeh K,McAlister FA,Ezekowitz JA,Fonarow GC,Johnson JA,Norris CM,Padwal RS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:A link between diabetes mellitus (DM) and heart failure (HF) has been well-recognized for more than a century. HF is also closely linked to abnormal glucose regulation (AGR) and insulin resistance (IR) in patients without DM and, similarly, these conditions commonly coexist. In epidemiological studies, each ...

journal_title：Journal of cardiac failure

authors： Mamas MA,Deaton C,Rutter MK,Yuille M,Williams SG,Ray SG,New J,Gibson JM,Neyses L

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Corin is a serine protease that cleaves pro-atrial and pro-B-type natriuretic peptides into biologically active hormones. The relationship between soluble plasma corin levels, plasma natriuretic peptide levels, myocardial structure and performance, and long-term clinical outcomes in the setting of chronic sy...

journal_title：Journal of cardiac failure

authors： Shrestha K,Troughton RW,Borowski AG,Yandle TG,Richards AM,Klein AL,Tang WH

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:This is the first study to examine the effect of acute (24-hour) beta-blocker withholding on ventilatory efficiency in patients with advanced chronic heart failure (CHF) during maximal incremental treadmill cardiopulmonary exercise test. METHODS AND RESULTS:Seventeen CHF patients were studied either 3 hours...

journal_title：Journal of cardiac failure

authors： Laveneziana P,Agostoni P,Mignatti A,Mushtaq S,Colombo P,Sims D,Uriel N,Jorde UP

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Large-scale clinical trials have demonstrated the benefits of cardiac resynchronization therapy (CRT) in patients with New York Heart Association (NYHA) Class III/IV heart failure, systolic left ventricular dysfunction, and a wide QRS. However, additional patient groups may also benefit from CRT. METHODS AN...

journal_title：Journal of cardiac failure

authors： Wein S,Voskoboinik A,Wein L,Billah B,Krum H

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The left ventricular assist device (LVAD) is a therapy for patients with end-stage heart failure, many of whom have a preexisting implantable cardioverter-defibrillator (ICD). We investigated whether the implantation of a LVAD affects ICD function. METHODS AND RESULTS:Patients implanted with a LVAD between ...

journal_title：Journal of cardiac failure

authors： Ambardekar AV,Lowery CM,Allen LA,Cannon AP,Cleveland JC Jr,Lindenfeld J,Brieke A,Sauer WH

更新日期：2010-04-01 00:00:00